Cell Line Development
At Samsung Biologics, we understand the importance of optimal cell line development in successfully navigating clinical trials and challenging regulatory approval processes. Our deep expertise and commitment to excellence help you reduce time to the market and keep costs low while achieving the best possible outcomes for your journey.
S-CHOice®
S-CHOice® builds on glutamine synthase (GS) knock-out Chinese hamster ovary (CHO) cell line technology and shows improved titers for standard monoclonal antibodies. The cell line also shows enhanced viability in a fed-batch study.
-
-
S-AfuCHO™
S-AfuCHO™
-
An upgraded S-CHOice® cell line to produce enhanced ADCC* activity antibodies
*ADCC: Antibody Dependant Cellular Cytotoxidity
-
Cell Line Development Workflow
Samsung Biologics’ Cell Line Development service offers clients a cell line process that combines world-class technology, a strategic mindset, and a collaborative spirit to deliver maximized titers and enhanced cell viability.
We also conduct multi-sequence evaluations during the CLD stage to identify the best candidates with proven quality. Samsung Biologics provides a proprietary cell line, S-CHOice, as well as CHOZN, one of the most robust cell lines in the industry.
Random Integration
3 months
- Transfection
- Plating(mini/bulk pool)
- Primary Screening
- Single CellCloning
- Secondary Screening
- Stability
Semi Targeted Integration (Transposase)
2 months
Random Integration
3 months
- Transfection
- Plating(mini/bulk pool)
- Primary Screening
- Single CellCloning
- Secondary Screening
- Stability
Semi Targeted Integration (Transposase)
2 months
Single Cell Cloning with Beacon® & C.SIGHT™
-
-
Beacon®
Beacon®
- Beacon® is a live cell-imaging and culture platform that enables high-throughput screening and advanced in-channel / in-pen assays to help scientists rapidly select relevant cells.
-
-
-
C.SIGHT™
C.SIGHT™
- The C.SIGHT™ is a benchtop single-cell sorter that can rapidly isolate cells into multi-well plates. It has a gentle dispensing system, imaging platform, and intuitive software, making it a cost-efficient tool for various cell biology applications.
-
