UPDATE | November 17, 2025

End-to-end saRNA manufacturing: Integrated development and in vivo potency

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End to end saRNA manufacturing Integrated development and in vivo potency


A self-amplifying RNA (saRNA) platform that is not only integrated from in vitro  transcription (IVT) optimization to LNP formulation, but also scalable, cost-efficient, and GMP-compliant? 


Samsung Biologics has developed a strategic, two-pronged workflow: 


  • an saRNA IVT platform that maximizes titer and integrity in a cost-efficient, GMP-aligned manner, and 
  • an LNP formulation platform that delivers mRNA/saRNA tailored to client-specific performance and targeting requirements.

End to end saRNA manufacturing Integrated development and in vivo potency


A self-amplifying RNA (saRNA) platform that is not only integrated from in vitro  transcription (IVT) optimization to LNP formulation, but also scalable, cost-efficient, and GMP-compliant? 


Samsung Biologics has developed a strategic, two-pronged workflow: 


- an saRNA IVT platform that maximizes titer and integrity in a cost-efficient, GMP-aligned manner, and 

- an LNP formulation platform that delivers mRNA/saRNA tailored to client-specific performance and targeting requirements.

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