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Fundamental Considerations for Bispecific Antibody-based Cell Line Development
The innovative dual specificity of bispecific antibodies opens a range of applications to serve the currently unmet needs of patients. However, due to the complexity of controlling advanced biotherapeutics, the industry still faces several challenges, including difficulty in maintaining the affinity of parental mAbs and mispairing. In this whitepaper, Seahee Kim, our principal scientist in cell line development, delves into the key considerations for upholding excellence in the quality of bispecific antibody-based cell line development.
The innovative dual specificity of bispecific antibodies opens a range of applications to serve the currently unmet needs of patients. However, due to the complexity of controlling advanced biotherapeutics, the industry still faces several challenges, including difficulty in maintaining the affinity of parental mAbs and mispairing. In this whitepaper, Seahee Kim, our principal scientist in cell line development, delves into the key considerations for upholding excellence in the quality of bispecific antibody-based cell line development.